Hanson, L. Å., 1997 Breast Feeding Stimulates the Infant Immune System. Science and Medicine 4:12-21.

Goldman, A. S., Thorpe, L. W., Goldblum, R. M, and Hanson, L. A. 1986. Review Article: Anti-Inflammatory Properties of Human Milk Acta Paediatrica Scandinavica 75:689-695.

Brunser, O., Espinoza, J., Figueroa, G., Araya, M., Spencer, E., Hilpert, H., Link-Amster, H., and Brüssow, H. 1992. Field Trial of an Infant Formula Containing Anti-rotavirus and Anti-Escherichia coli Milk Antibodies from Hyperimmunized Cows. Journal of Pediatric Gastroenterology and Nutrition 15:63-72.

Campbell, B., and Petersen, W. E. 1964. Immune Milk. Journal of Immune Milk 1:3-28.

Davidson, G. P., Daniels, E., Nunan, H., Moore, A. G., Whyte, P. B. D., Franklin, K., McCloud, P. I., and Moore, D. J. 1989. Passive Immunisation of Children with Bovine Colostrum containing Antibodies to Human Rotavirus The Lancet 2:709-712.

Ebina, T., Sato, A. Umezu, K, Ishida, N., Ohyama, S. Oizumi, A., Aikawa, K., Katagiri, S., Katsushima, N., Imai, A., Kitaoka, S., Suzuki, H., and Konno, T. 1985. Prevention of Rotavirus Infection by Oral Administration of Cow Colostrum Containing Antihumanrotavirus Antibody Medical Microbiology and Immunology 174:177-185.

Fayer, W., Perryman, L. E., and Riggs, M. W. 1989b. Hyperimmune Bovine Colostrum Neutralizes Cryptosporidium Sporozoites and Protects Mice Against Oocyst Challenge Journal of Parasitology 75:151-153.

Golay, A., Ferrara, J-M., Felber J-P., and Schneider, H. 1990. Cholesterol-lowering effect of skim milk from immunized cows in hypercholesterolemic patients American Journal of Clinical Nutrition 52:1014-1019.

Mietens, C. and Keinhorst, H. 1979. Treatment of Infantile E. coli Gastroenteritis with Specific Bovine anti-E. coli Milk Immunoglobulins European Journal of Pediatrics 132:239-252.

Ormrod, D. J., and Miller, T. E. 1991. The Anti-Inflammatory Activity of a Low Molecular Weight Component Derived from the Milk of Hyperimmunized Cows Agents and Actions 32:160-166.

Owens, W. E., and Nickerson, S. C. 1988 Evaluation of an Anti-Inflammatory Factor Derived from Hyperimmunized Cows (42832) Proceedings Society Experimental Biology and Medicine 190:79-86.

Sharpe, S. J., Gamble, G. D., and Sharpe, D. N. 1994. Cholesterol-lowering and Blood Pressure Effects of Immune Milk American Journal of Clinical Nutrition 59: 929-934.

Smith, C. M. 1964. Immune Milk in the Treatment of the Rheumatoid Arthritis Syndrome Journal of Immune Milk 1:37-42.

Ormrod, D. J., and Miller, T. E. 1993. Milk from Hyperimmunized Dairy Cows as a Source of a Novel Biological Response Modifier Agents and Actions (Special Conference) 38:C146-C149.

Ambekar, R. and Chungi, V. Hyperimmune Egg: Its Ability to Maintain Weight and Lean Muscle Mass in Individuals with Cachexia (unpublished)

Chou, H-T., Huang, S-C., and Ip, S-W. A Study of the Efficacy and Safety of Stolle Immune Milk (S-200) in the Treatment of Mild to Moderate Essential Hypertension. (unpublished)

Tsubokura, K. Berndtson, E., Bogstedt, A., Kaijser, B., Kim, M., Ozeki, M. and Hammarström, L. 1997. Oral Administration of Antibodies as Prophylaxis and Therapy in Campylobacter jejuni-Infected Chickens. Clinical Experimental Immunology 108:451-455.

Kuroki, M., Ohta, Y., Ikemoris, R.C., Peralta, R.C., Yokoyama, H. and Kodma, Y. 1994. Passive Protection Against Bovine Rotavirus in Calves by Specific Immunoglobulins from Chicken Egg Yolk. Archives Virology 138:141-148.

Bartz, C. R., Conklin, R. H., Tunstall, C. B., and Steele, J. H. 1980. Prevention of Murine Rotavirus Infection with Chicken Egg Yolk Immunoglobulins Journal of Infectious Diseases 142:439-441.

Kühlmann, R., Wiedemann, V., Schmidt, P., Wanke, R., Linckh, E., and Lösch, U. 1988. Chicken Egg Antibodies for Prophylaxis and Therapy of Infectious Intestinal Diseases, I. Immunization and Antibody Determination Journal of Veterinary Medicine 35:610-616.

Tacket, C.O., Losonsky, G., Link, H. Hoang, Y., Guesry, P., Hilpert, H. and Levine, M.M. 1988. Protection by Milk Immunogloubulin Concentrate Against Oral Challenge with Enterotoxigenic Escherichia coli. New England Journal of Medicine 318:1240-1243.

Ormrod, D. J., and Miller, T. E. 1993. Milk from Hyperimmunized Dairy Cows as a Source of a Novel Biological Response Modifier Agents and Actions (Special Conference) 38:C146-C149.

Hamada, S., Horikoshi, T., Minami, T., Kawabata, S., Hiraoka, J., Fujiwara, T., and Ooshima, T. 1991. Oral Passive Immunization against Dental Caries in Rats by Use of Hen Egg Yolk Antibodies Specific for Cell-Associated Glucosyltransferase of Streptococcus mutans Infection and Immunity 59:4161-4167.

Tsunemitsu, H., Shimizu, M., Hirai, T., Yonemichi, H., Kudo, T., Mori, K., and Onoe S. 1989 Protection against Bovine Rotaviruses in Newborn Calves by Continuous Feeding of Immune Colostrum Japanese Journal of Veterinary Science 51:300-308.

Collins, N. F., Halbur, T., Schwenck, W. H., Hoogeveen, P., Pierce, R. L., Behan, R. W., and Pankratz, D. 1988. Duration of Immunity and Efficacy of an Oil Emulsion Escherichia coli bacterin in cattle American Journal of Veterinary Research 49:674-677.

Tzipori, S., Roberton, D., and Chapman, C. 1986. Remission of Diarrhea Due to Cryptosporidiosis in an Immunodeficient Child Treated with Hyperimmune Bovine Colostrum British Medical Journal 293:1276-1277.

Hammarström, L., Gardulf, A., Hammarström, V., Janson, A. Lindberg, K., and Smith, C. I. E. 1994. Systemic and Topical Immunoglobulin Treatment in Immunocompromised Patients. Immunological Reviews 139, 43-70.

Losonsky, G. A., Johnson, J. P., Winkelstein, J. A., and Yolken, R. H. 1985. Oral Administration of Human Serum Immunoglobulin in Immunodeficient Patients with Viral Gastroenteritis Journal of Clinical Investigation 76:2362-2367.

Kowalczyk, K., Daiss, J., Halpern, J., and Roth, T. F. 1985. Quantitation of Maternal-Fetal IgG Transport in the Chicken Immunology 54:755-762.

Rose, E. M., Orlans, E., and Buttress, N. 1974. Immunoglobulin Classes in the Hen’s Egg: Their Segregation in Yolk and White European Journal of Immunology 4:521-523.

Lo, C.W. and Kleinman, R. E. 1996. Infant Formula, Past and Future: Opportunities for Improvement. American Journal Clinical Nutrition. 63:646S-650S.

Newman, J. 1995 How Breast Milk Protects Newborns Scientific American 273:76-79.

Yolken, R., Losonsky, G. A., Vonderfecht, S., Leister, F. and Wee, S-B. 1985. Antibody to Human Rotavirus in Cow’s Milk New England Journal of Medicine 312:605-610.

Bade, H. and Stegemann, H. 1984. Rapid Method of Extraction of Antibodies from Hen Egg Yolk Journal of Immunological Methods 72:421-426.

Goldman, A. S. 1993 The Immune System of Human Milk: Antimicrobial, Antiinflammatory and Immunomodulating Properties Peiatric Infectious Disease Journal 12:664-671.

Otake, S., Nishihara, Y., Makimura, M., Hatta, H., Kim, M., Yamamoto, T., and Hirasawa, M. 1991. Protection of Rats Against Dental Caries by Passive Immunization with Hen-egg yolk Antibody (IgY) Journal of Dental Research 70: 162-166.

Wilborn, W. H.(a) 1991-1992. Microscopic Evaluation of the Effects of Non-Immune (Control) Eggs, Immune (S-100) Eggs, and Mixed Eggs (Blend of Control and S-100 Eggs) on The Cardiovascular System of NZW Rabbit 1-29. (unpublished).

Wilborn, W. H. (b) 1992-1992. Comparison of the Effects of Control Whole Eggs, Immune Whole Eggs, and Immune Egg Components (Yolk, White, and Immunoglobulin Y Yolk Protein) on NZW Rabbits Challenged with a High Cholesterol Diet 1-16. (unpublished).

Wilborn, W. H. (c) undated. Effect of Immune Egg Yolk and Egg White on High Cholesterol Diets. Protocol # EGCHOL-2 103-109. (unpublished).

Wilborn, W. H. (d) undated. Effect of Immune Egg Protein on Serum Cholesterol in Rabbits on Atherogenic Diets. Protocol # EGCHOL-3 1-11. (unpublished).

Polson, A., Coetzeer, E., Kruger, J., von Maltzahn, E., and van der Merwe, K. J. 1985. Improvements in the Isolation of IgY from the Yolks of Eggs laid by Immunized Hens. Immunological Investigations 14:323-327.

Barnes, G. L., Hewson, P. H., McLellan, J. A., Doyle, L. W., Knoches, A. M. L., and Kitchen, W. H. 1982. A Randomized Trial of Oral Gamma globulin in Low-Birth-Weight Infants Infected with Rotavirus The Lancet, 1:1371-1373.

Casswall T. H., Hammarstrom, L., Veress, B., Nord, C. E., Bogstedt, A., Brockstedt, U., and Dahlstrom, K. A. 1996. Oral IgA-IgG Treatment of Chronic Non-Specific Diarrhoea in Infants and Children. Acta Paediatrica Scandinavica 85:1126-1128.

Ungar, B. L. P., Ward, D. J., Fayer, R., and Quinn C. A. 1990 Cessation of Cryptosporidium-Associated Diarrhea in an Acquired Immunodeficiency Syndrome Patient After Treatment with Hyperimmune Bovine Colostrum Gastroenterology 98:486-489.

Cama, V. A., and Sterling C. R. 1991. Hyperimmune Hens as a Novel Source of Anti-Cryptosporidium Antibodies Suitable for Passive Immune Transfer Journal of Protozoology 38:42S-43S.

Ebina, T., Tsukada, K., Umezu, K., Nose, M., Tsuda, K., Hatta, H., Kim, M., and Yamamoto, T. 1990. Gastroenteritis in Suckling Mice Caused by Human Rotavirus Can be Prevented with Egg Yolk Immunoglobulin (IgY) and Treated with a Protein-Bound Polysaccharide Preparation (PSK). Microbiological Immunology 34:617-629.

Heckert,R. A., Saif, L. J. Mengel, J. P. and Myers, G. W. 1991. Mucosal and Systemic Antibody Responses to Bovine Coronavirus Sturctural Proteins in Experiemntally Challenge-Exposed Calves Fed Low or High Amounts of Colostral Antibodies. American Journal of Veterinary Research 51:700-708.

Hiraga, C., Kodama, Y., Sugiyama, T., and Ichikawa, Y. 1990. Prevention of Human Rotavirus Infection with Chicken Egg Yolk Immunoglobulins Containing Rotavirus Antibody in Cat Journal of Japanese Association of Infectious Disease 64:118-123.

Kuroki, M., Ikemori, Y., Yokoyama, H., Peralta, R. C., Icatlo, F. C., and Kodama, Y. 1993. Passive Protection Against Bovine Rotavirus-Induced Diarrhea in Murine Model by Specific Immunoglobulins from Chicken Egg Yolk Veterinary Microbiology 37:135-146.

Nagy, B. 1980. Vaccination of Cows with a K99 Extract to Protect Newborn Calves Against Experimental Enterotoxic Colibacillosis Infection and Immunity 27:21-24.

Saif, L., Redman, D. R., Smith, K. L., and Theil, K. W. 1983. Passive Immunity to Bovine Rotavirus in Newborn Calves Fed Colostrum Supplements from Immunized or Nonimmunized Cows Infection and Immunity 41:1118-1131.

Yokoyama, H., Umeda, K., Peralta, R. C., Hashi, F., Icatlo, F. C., Kuroki, M., Ikemori, Y., and Kodama, Y. 1998a Oral Passive Immunization Against Experimental Salmonellosis in Mice Using Chicken Egg Yolk Antibodies Specific for Salmonella enteritidis and S. typhimurium. Vaccine 16:388-393.

Yokoyama, H., Peralta, R.C., Umeda, K., Hashi, T., Icatlo, F.C., Kuroki, M., Ikemori, Y., and Kodama, Y. 1998b. Prevention of Fatal Salmonellosis in Neonatal Calves, Using Orally Administered Chicken Egg Yolk Salmonella-Specific Antibodies. American Journal Veterinary Research 59:416-420.

Yokoyama, H., Peralta, R. C., Sendo, S., Ikemori, Y., and Kodama, Y. 1993 Detection of Passage and Absorption of Chicken Egg Yolk Immunoglobulins in the Gastrointestinal Tract of Pigs by Use of Enzyme-Linked Immunosorbent Assay and Flurescent Antibody Testing. American Journal of Veterninary Research 54:867-872.

Yokoyama, H., Peralta, R. C., Diaz, R., Sendo, S., Ikemori, Y., and Kodama, Y. 1992 Passive Protective Effect of Chicken Egg Yolk Immunoglobulins against Experimental Enterotoxigenic Escherichia coli Infection in Neonatal Piglets Infection and Immunity 60:998-1007.

Yolken, R. H., Leister, F., Wee, S-B., Miskuff, R., and Vonderfecht, S. 1988. Antibodies to Rotaviruses in Chickens’ Eggs: A Potential Source of Antiviral Immunoglobulins Suitable for Human Consumption Pediatrics 81:291-295.

Ross, R., 1999. Atherosclerosis-An Inflammatory Disease. New England Journal Medicine 340:115-126.

Fujinami, R. S. 1992. Molecular Mimicry. In The Autoimmune Diseases II. N.R.Rose, and I.R. Mackay, eds. Academic Press, Inc. NY pp.153-169.

See, D. M. 1998 Complementary Therapies for Arthritis Journal American Nutraceutical Association 1:7-14.

Luster A. D. 1998 Chemokines-Chemotactic Cytokines That Mediate Inflammation New England Journal of Medicine 338:436-445.

Johnson, R. W. 1997 Inhibition of Growth by Pro-Inflammatory Cytokines: An Integrated View Journal Animal Sciences 75:1244-1255.

Johnson, R. W., Arkins, S., Dantzer, R., and Kelley, K. W. 1997 Hormones, Lymphohemopoietic Cytokines and the Neuroimmmune Axis Comparative Biochemical Physiology 116A:183-201.

Bayard, B. L. and James, M. A. 1987 Hyperimmune Bovine Colostrum Inefficacious as Multiple Sclerosis Therapy in Double-Blind Study Journal American Dietetic Association 87:1388-1390.

Ikemori, Y., Ohta, Masashi,Umeda, K., Icatlo F. C., Kuroki, M.,Yokoyama, H.,and Kodama, Y. 1997 Passive Protection of Neonatal Calves Against Bovine Coronavirus-Induced Diarrhea by Administration of Egg Yolk or Colostrum Antibody Powder. Veterinary Microbiology 58:105-111.

Sugita-Konishi, Y., Shibata, K. Yun Seob S., Hara-Kudo, Y. .,Yamaguchi, K., and Kumagai,S. 1996. Immune Functions of Immunoglobulin Y Isolated from Egg Yolk of Hens Immunized with Various Infectious Bacteria. Bioscience, Biotechnology and Biochemistry 60:886-888.

Ebina, T. 1996 [Supplement]. Prophylaxis of Rotavirusgastroenteritis Using Immunoglobulin. Archives Virology 12:217-223.

Larsson, A., Balow, R. M., Lindahl, T. L., and Forsberg, P.O. 1993 Chicken Antibodies: Taking Advantage of Evolution-A Review. Poultry Sciences 72:1807-1812.

Gassmann, M. Thommes, P.,Weiser, T., and Hubscher, U. 1990.Efficient Production of Chicken Egg Yolk Antibodies Against a Conserved Mammalian Protein. FASEBJournal 4:2528-2532.

Ungar, B. L. P., Ward, D. J., Fayer, R. and Quinn, C. A. 1990. Cessation of Cryptosporidium-Associated Diarrhea in an Acquired Immunodeficiency Syndrome Patient after Treatment with Hyperimmune Bovine Colostrum. Gastroenterology 98:486-489.

Freedman, D. J., Tacket, C. O., Delehanty, A., Maneval, D. R., Nataro, J.and Crabb, J.H. Milk Immunoglobulin with Specific Activity Against Purified Colonization Factor Antigens Can Protect Against Oral Challenge with Enterotoxigenic Escherichia coli. Journal of Infectious Diseases 177:662-667.

McClead, R. E., Butler, T.,and Rabbani, G. H. 1988. Orally Administered Bovine Colostral Anti-Cholera Toxin Antibodies: Results of Two Clinical Trials. American Journal of Medicine 85:811-816.

Howe, H. A. 1962 The Quantitation of Polio Virus in the Human Alimentary Tract with reference to Coexisting Levels of Homologous Serum Neutralising Antibody. American Journal of Hygiene 75:1-8.

Walker, W. A., Isselbacher, K. J. and Bloch, K.J. 1972. Intestinal Uptake of Macromolecules: Effect of Oral Immunisation. Science 177:608-610.

Newby, T. J. and C. R. Stokes. 1984. The Intestinal Immune System and Oral Vaccination. Veterinary Immunology and Immunopathology 6:67-105.

Golay, A., Ferrara, J-M., Felber, J-P., and Schneider, H. 1990 Cholesterol-Lowering Effect lof Skim Milk from Immunized Cows in Hypercholesterolemic Patients. American Journal of Clinical Nutrition 52:1014-1019.

Sharpe, S. J., Gamble, G. D. and Sharpe, D. N. 1994 Cholesterol-Lowering and Blood Pressure Effects of Immune Milk. American Journal of Clinical Nutrition 59:929-934.

O’Farrelly, C., Branton, D. and Wanke, C. A. 1992 Oral Ingestion of Egg Yolk Infection and Immunity 60:2593-2567.

Shimizu, M., Nagashima.,H.,Sano, K.,Hashimoto, K. Ozeki, M., Tsuda, K, and Hatta, H. 1992 C. A. 1992 Molecular Stability of Chicken and Rabbit Immunoglobulin G Bioscience, Biotechnology and Biochemistry 56:270-274.

Janson, A. K., Smith, C. I. E. and Hammarström, L. 1995. Biological Properties of Yolk Immunoglobulins In Advances in Mucosal Immunology eds. Mestecky, J., Russell, M. W. Jackson, S., Michalek, S. M., Tlaskalova-Hogenova, H., and Sterzl, J. eds Plenum Press,. NY, London pp.685-690.

Hadge, D. and Ambrosius, H. 1984 Evolution of low molecular weight immunoglobulins. IV. IgY-like immunoglobulins of birds, reptiles and amphibians, precursors of mammalian IgA. Molecular Immunology 21:699-707.

Michaels, R. H. 1965 Studies of Antiviral Factors in Human Milk and Serum. Journal of Immunology 94:262-271.